The developing fetus and the juvenile animal did not appear to be more sensitive than the adult animal to the effects of acephate. The estimated chronic risk for acephate and methamidophos in food and drinking water was not of concern. Subsequently, the technical registrants of methamidophos voluntarily discontinued all methamidophos products and the registrations expired in 2012. Most uses of acephate have value in the food and non-food agriculture industry and are not of concern to human health or the environment when used according to revised label directions. Acephate 90 WDG is a dispersible granule used as an insecticide for control of pests on selected agricultural crops and in listed non-crop areas. Acephate is an insecticide that belongs to the organophosphate group of chemicals.It is typically used as a foliar spray against chewing and sucking insects, such as aphids, leaf miners, Lepidopterous larvae, sawflies, and thrips on fruits, vegetables, potatoes, sugarbeet, vines, rice, hops, ornamentals, and greenhouse crops like peppers and cucumbers. Acephate is unlikely to affect your health when used according to revised label directions. The active ingredient in Acephate 90 WDG is absorbed by plants via the roots and foliage to provide systemic control of feeding insects. It also can be applied as a separate treatment using enough water to give adequate coverage of the seed. ACEPHATE 750 SP MATERIAL SAFETY DATA SHEET Page 1 of 6 1. Acephate is registered for application to a wide variety of trees using several application methods. Food containing a pesticide residue that does not exceed the established MRL does not pose an unacceptable health risk. The estimated acute exposure for acephate and methamidophos in food and drinking water was of concern based on initial modelled drinking water concentrations. Changes to label statements to include precautionary statements for sites with characteristics that may be conducive to runoff and when heavy rain is forecasted are required to reduce the potential for acephate in runoff to adjacent aquatic habitats. This document (Proposed Re-evaluation Decision PRVD2019-04, Acephate and Its Associated End-use Products) presents revisions to the proposed regulatory decision for the re-evaluation of acephate (PRVD2016-01) with risk mitigation measures to protect the environment along with updates to the environmental evaluation on which the proposed decision was based. For outdoor and perimeter spray excluding residental turf with Acephate 97UP Insecticide the rate is 1. To protect the environment, the following measures are proposed: Proposed label amendments resulting from these environmental mitigation measures are presented in Appendix II of PRVD2019-04. Acephate was mildly irritating to eyes and skin and was not found to cause an allergic skin reaction. 610-491-2800 The Food and Drugs Act prohibits the sale of adulterated food, which includes food containing a pesticide residue that exceeds the established maximum residue limit (MRL). Proposed protective measures to reduce worker exposure require consultation with user groups to determine their acceptability. This label direction can be removed if data are submitted to estimate exposure and demonstrate no risks of concern. The PMRA will accept written comments on Proposed Re-evaluation Decision PRVD2016-01, Acephate up to 60 days from the date of publication of PRVD2016-01. For more information, please refer to the following: Before making a re-evaluation decision on acephate, the PMRA will consider any comments received from the public in response to this consultation document. In case of contact with skin, wash with soap and water. The estimated acute exposure ranged from 600-2900% of the acute reference dose (ARfD) for acephate and 1100-5400% of the ARfD for methamidophos for the various population subgroups. Although the postapplication risk assessment for the horticultural scenarios identified risks of concern based on the current use pattern, the risk estimates include a number of uncertainties. With refined modelled drinking water concentrations, the estimated chronic exposure ranged from 1-3% of the ADI for acephate and 1-2% of the ADI for methamidophos for the various population subgroups. The public, including the registrant and stakeholders are encouraged to submit additional information that could be used to refine the environmental risk assessment during the 90-day public consultation periodFootnote 1 upon publication of this proposed re-evaluation decision. 2 oz per gallon of water. 14225 PEST CONTROL PRODUCTS ACT Arvesta Corporation Tomen Canada, Inc. Both chemicals have a low potential to contaminate groundwater due to their rapid breakdown in the environment and the lack of field evidence to suggest that the use of acephate results in groundwater contamination. Human exposure to acephate and methamidophos was estimated from residues in treated crops and drinking water, including the most highly exposed population subgroups (for example, infants <1 years, children 1-2 years). Insecticide. ORTHENE® 97 insecticide's active ingredient, acephate, is readily absorbed by plant roots and foliage to give both contact activity and systemic control of feeding insects in high-value vegetable crops as well as soybean, cotton and tobacco. These label directions can be removed if data are submitted to estimate exposure and demonstrate no risks of concern. When using this formulation, target MOEs were not achieved for most scenarios based on current label directions for various application equipment. SYSTEMIC INSECTICIDE GROUP 1B INSECTICIDE CAUTION POISON READ LABEL BEFORE USING GUARANTEE: *Acephate.....75% NET CONTENTS: 1.5 kg REGISTRATION NO. These types of applications are currently registered for use on various trees and ornamentals, and in Christmas tree plantations, farm woodlots, nurseries, shelter belts, right of ways and municipal parks. MRLs are specified for acephate and methamidophos on a wide range of commodities. What is the proposed Re-evaluation Decision? 12U-102 Acephate 97UP Insecticide Revision date 05-Nov-2015 Precautionary Statements - Prevention Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product Wear protective gloves/protective clothing/eye protection/face protection Do not get in eyes, on skin, or on clothing To reduce food and drinking water risk concerns: application rate and maximum number of applications per year are proposed to be reduced, and minimum application intervals are proposed to be increased for certain crops. 610-491-2800 In the absence of data to estimate risk, a label direction specifying “Not for use with fogging equipment” is required. Some naturally occurring insect biotypes resistant to TITAN Acephate 970 SG Insecticide and other Group 1B insecticides may exist through normal genetic variability in any insect population. Acephate can enter nontarget terrestrial and aquatic habitats through spray drift and can enter aquatic habitats through runoff and leaching. Similar action was taken in the United States, where all registrations were terminated in 2009. NEW Find here Acephate, Acetamidophos manufacturers, suppliers & exporters in India. In the absence of data to estimate risk, label directions specifying “Not for use with hand-held mist blowers” and “Automated mist blowers are permitted” are required. King of Prussia, PA 19406. It was of low acute toxicity via the dermal and inhalation routes of exposure. Additionally, cartridge implants provide protection to trees for a period of 10 to 12 weeks for heavy infestations and up to 18 weeks for light infestations, replacing the need for several foliar applications. Canada restricts uses of acephate The registration of certain uses of insecticide acephate in Canada is proposed for cancellation. Currently, the main product available for foliar applications in various agricultural and horticultural scenarios is packaged as a soluble powder. The active ingredient in Acephate 97UP is acephate, a water-soluble insecticide readily absorbed by plant roots and foliage to give systemic control of feeding insects. Pest Management Regulatory Agency 8 January 2016 ISSN: 1925-0967 (PDF version) Catalogue number: H113-27/2016-1E-PDF (PDF version). Acephate appears as a white solid. Toxicology studies in laboratory animals describe potential health effects from varying levels of exposure to a chemical and identify the dose at which no effects are observed. Pending the completion of the risk assessment for methamidophos, the PMRA implemented interim mitigation measures for acephate products in 2007 (REV2007-02). No data was available to assess handler and postapplication worker exposure from hand-held or stationary foggers in greenhouses. Proposed REIs range from 12 hours to 20 days. Environmental risks to birds and small wild mammals were identified for all outdoor foliar uses applied by mist blowers or airblast application equipment and were not shown to be acceptable. Used as a contact and systemic insecticide. Pesticides and pest management consultations, Consultation on acephate and its associated end-use products – Updated environmental risk assessment, Proposed Re evaluation Decision PRVD2019-04, Proposed Re-evaluation Decision PRVD2019-04, Acephate and Its Associated End-use Products, Proposed Regulatory Decision for Acephate. No data was available to assess handler exposure from hand-held mist blowers for mist application in greenhouses. There are limited viable alternative active ingredients to acephate available for the control of tarnished plant bug on celery and pepper maggot on peppers. The transformation product methamidophos was included in the risk assessment as it can be more toxic to nontarget organisms than acephate. If the pests cannot be adequately managed under the new application timing, these claims may be removed from the labels. The active ingredient in ACEPHATE 75 SP is acephate, a water soluble insecticide readily absorbed by plant roots and foliage to give systemic control of feeding insects. Postapplication occupational risk assessments consider exposure to workers entering treated sites in agriculture and other scenarios. For foliar applications to trees and ornamentals in residential areas, quantitative estimates of exposure and risk were determined for both acephate and methimidophos based on the available data, or using standard defaults in the absence of data. It is also used to control ants, wasps, cockroaches, earwigs and other insects in and around residences, institutions, and … To update Toxicological Information on labels: additional information about symptoms and treatment for exposed individuals are required. Crops with minor use registrations identified as having particular value are the following: aphids on celery; blackheaded fireworm on cranberry; and the pipette and syringe application method to trees for the control of sucking and chewing insects. At the time that the re-evaluation decision is made, the PMRA will publish an Evaluation Report on acephate in the context of this re-evalulation decision (based on the Science Evaluation of Proposed Re-evaluation Decision PRVD2016-01, Acephate). An acceptable daily intake is an estimate of the level of daily exposure to a pesticide residue that, over a lifetime, is believed to have no significant harmful effects. When using the pellet formulation with the various application equipment, the calculated MOEs meet the target MOE with minimal mitigation, such as baseline PPE for most crops and a respirator for a few specific uses. With refined modelled drinking water concentrations, the estimated acute exposure ranged from 23-49% of the ARfD for acephate and 33-56% of the ARfD for methamidophos for the various population subgroups. Cancellation of airblast and outdoor mistblower applications, which are currently registered for use on various trees and ornamentals, and in Christmas tree plantations, farm woodlots, nurseries, shelter belts, right of ways and municipal parks, Cancellation of the highest foliar application rate (resulting from the cancellation of applications by airblast/mistblower, the only method for which the highest rate is registered), Uses in farm woodlots, shelter belts, rights of way and municipal parks are limited to spot treatments using hand-held equipment only, Precautionary and hazard statements to inform users of the toxicity and potential risk of acephate to pollinators, beneficial arthropods, birds, mammals, and aquatic organisms, Label statements directing users to avoid application during periods of bloom or during the 9-day period before crop bloom for crops that are attractive to pollinators (or for other crops when using managed bees for pollination services), Statements directing users that tree injection applications must be made after the blooming/pollen shedding period, A label statement directing users not to discharge acephate-contaminated effluent from greenhouses into aquatic environments, Precautionary label statements informing users of ways to reduce the potential for runoff. ACEPHATE 97UP is an insecticide for control of pests on selected agricultural crops and in certain non-crop areas. Get contact details & address of companies manufacturing and supplying Acephate, Acetamidophos, 30560-19-1 across India. Any insect population may contain individuals naturally resistant to ACEPHATE 750 SP and other group code 1B insecticides. The pellet formulation has since been registered for use on tobacco only. To obtain a full copy of Proposed Re-evaluation Decision PRVD2019-04, Acephate and Its Associated End-use Products please contact our publications office. Where no specific MRL has been established, a default MRL of 0.1 ppm applies, which means that pesticide residues in a food commodity must not exceed 0.1 ppm. Occupational postapplication risks are not of concern based on revised label directions. Therefore, mitigation measures are required in order to reduce potential exposure of nontarget organisms and reduce environmental risks. Acephate 97UP contains a water-soluble systemic insecticide which helps to reduce injury to cotton seedlings by several insects. The available studies did not indicate a concern for an effect on the immune system. Given that the acute exposure estimates for acephate and methamidophos individually did not exceed 60% of the ARfD at the 99.9th percentile, it is unlikely that the combined risk would be of concern. Pesticide MRLs are established through the evaluation of scientific data under the Pest Control Products Act. Acephate is an organophosphate insecticide. Therefore, acute exposure from acephate and methamidophos in food and drinking water are not of concern provided that the mitigation measures outlined in Section 3.4.1 of PRVD2016-01 are implemented. After a re-evaluation of the organophosphate insecticide acephate, Health Canada’s Pest Management Regulatory Agency (PMRA), under the authority of the Pest Control Products Act, is proposing continued registration of certain products containing acephate for the sale and use in Canada. When assessing health risks, two key factors are considered: The dose levels used to assess risks are established to protect the most sensitive human population (for example, children and nursing mothers). Methamidophos, the primary metabolite of acephate, was not fully considered in the acephate risk assessment since a concurrent risk assessment for methamidophos as a registered active ingredient at the time was being conducted. Acephate 97UP is an insecticide for control of pests on selected agricultural crops and in certain non-crop areas. Since the 2007 interim mitigation measures for acephate, the PMRA has updated the risk assessments considering new data, inclusion of methamidophos in the risk assessments, and the pellet formulation as a potential replacement of the soluble powder formulation. This document (PRVD2019-04) is subject to a 90-day public consultation period, during which the public including the pesticide manufacturers and stakeholders may submit written comments and additional information to the PMRA Publications Section. You will not receive a reply. Under controlled laboratory conditions, acephate and methamidophos can be toxic to some nontarget species such as bees, beneficial insects, birds, wild mammals, aquatic invertebrates, amphibians and fish. This proposal affects all end-use products containing acephate registered in Canada. Active Ingredients: Acephate 98% Stakeholder feedback is therefore critical in determining whether these pests are expected to be controlled under the proposed restrictions. Registered pesticide product labels include specific instructions for use. Acephate also is important to the management of resistance to other active ingredients registered for the control of woolly apple aphid and woolly elm aphid on Saskatoon berry and omnivorous leaf roller on greenhouse roses. Acephate is a systemic insecticide with long lasting residual activity (typically 10 to 21 days), which is absorbed and transported throughout the plant, thereby protecting the whole plant. Several MRL changes for acephate and methamidophos are proposed as a result of this re-evaluation, as indicated in Section 9.1.1.3 of PRVD2016-01. Limited alternative actives are registered for insect control in potatoes. Thus, dietary exposure and risk assessments were conducted for both acephate and methamidophos. Occupational postapplication risks are not of concern if proposed protective measures are followed. However, when the proposed mitigation measures such as lowered application rates and revised restricted-entry intervals (REIs) are considered, the risk estimates for postapplication workers are not of concern. In addition, the test data on which the decision is based will also be available for public inspection, upon application, in the PMRA’s Reading Room (located in Ottawa). Due to the risk concerns identified, mitigation measures and refinements were considered in the modelled drinking water concentrations. The generation of additional data may refine the current risk assessment and may potentially reduce the proposed REIs. Acephate -- 97.4% Orthene 97 WP Turf Tree Ornamental - 1can (.773LB) is the proven choice for key insect control in dozens of high value vegetable crops as well as soybeans, cotton and tobacco. As a result of the re-evaluation of acephate, further risk mitigation measures for product labels are being proposed. Directions include risk mitigation measures to protect human health and the environment that must be followed by law. Only uses for which the exposure is well below levels that cause no effects in animal testing are considered acceptable for registration. If you would like to comment, please request the full consultation document. Each MRL value defines the maximum concentration in parts per million (ppm) of a pesticide allowed in/on certain foods. The Forest industry uses it on pine trees and Christmas trees. Active ingredients with prolonged residual activity are of particular benefit to growers when insect pests emerge over extended periods of time such as due to cool weather, or when insect pest populations remain at economically damaging levels for long periods due to overlapping generations. Details on these considerations are noted in Section 3.4.1 of Proposed Re-evaluation Decision PRVD2016-01, Acephate. You will not receive a reply. Insects eat the foliage of the plants and die. The Overview describes the regulatory process and key points of the evaluation, while the Science Evaluation provides detailed technical information on the assessment of acephate. It is used primarily for control of aphids, including resistant species, in vegetables (e.g. Proposed Re-evaluation Decision PRVD2016-01, Acephate is a consultation document that summarizes the science evaluation for acephate and presents the reasons for the proposed re-evaluation decision. No additional information is required at this time. For enquiries, contact us. The cartridge implant and trunk injection application methods are of value for insect control on high value trees where applications of foliar sprays are not feasible such as in urban areas, or trees close to ecologically sensitive habitats. You can use it for research or reference. The mitigation measures considered included the removal of acephate use on potatoes, the reduction of application rates and number of applications per season, as well as increasing minimum application intervals for several crop uses. IDENTIFICATION OF THE SUBSTANCE Product Name ACEPHATE 750 SP Insecticide Common Name Acephate Active Ingredient: Acephate (BSI, E-ISO, ANSI, ESA, BPC), (m)(F-ISO, JMAF) Chemical Name: O,S-dimethyl acetylphosphoramidothioate (IUPAC) CAS N o.: 30560-19-1 Risks to birds and small wild mammals were also identified for broadcast foliar spraying in farm woodlots, shelterbelts, right of ways and municipal parks and were not shown to be acceptable. Acephate is an organophosphate insecticide. Acephate and its major transformation product, methamidophos, break down quickly in soil and water and are not expected to persist in the environment. Residues in drinking water were based on modelling data. Occupational (mixer/loader/applicator) risks are not of concern when products are used according to revised label directions and/or products are formulated as a pellet and encapsulated tree implant. Under the authority of the Pest Control Products Act , all registered pesticides must be regularly re-evaluated by Health Canada’s Pest Management Regulatory Agency (PMRA) to ensure that they continue to meet current health and environmental safety standards and continue to have value. While formulating these measures, the PMRA considered the measures proposed in PACR2004-40, the comments received on PACR2004-40, as well as the additional data and use information from the registrant. When used according to the revised label directions, acephate does not pose an unacceptable risk to the environment. Use on potatoes is proposed for cancellation. A science-based approach will be applied in making a final decision on acephate. Protecting Your Health and the Environment, o reflect the current registered use pattern for acephate, to account for proposed mitigation measures, and to ensure that residues in food do not pose any health risk concerns. It also controls leaf miners, caterpillars, sawflies, thrips, and spider mites in the previously stated crops as well as turf, and forestry. Reference doses define levels to which an individual can be exposed over a single day (acute) or lifetime (chronic) and expect no adverse health effects. 4.5 out of 5 stars 10. The changes to the MRLs are proposed to account for the phase-out of all methamidophos uses,to reflect the current registered use pattern for acephate, to account for proposed mitigation measures, and to ensure that residues in food do not pose any health risk concerns. King of Prussia, PA 19406. To obtain a full copy of Proposed Re-evaluation Decision PRVD2016-01 Acephate please contact our publications office. Use of acephate may avoid repeated applications of non-systemic and contact insecticides. Generally, dietary exposure from food and water is not of concern if it is less than 100% of the acute reference dose or chronic reference dose (acceptable daily intake). 630 Freedom Business Center, Suite 402. This page is a summary of the consultation document. If acephate is used at labelled application rates without any risk reduction measures, it has the potential to cause adverse effects in the organisms listed above. “Decision statement” as required by subsection 28(5) of the Pest Control Products Act. Acephate 97UP can be mixed in the slurry tank with most of the fungi- cide seed treatments in common use. potatoes, carrots, greenhouse tomatoes, and lettuce) and in horticulture (e.g. Acephate contributes to pest management in the ornamental industry. A pellet formulation was determined to be an acceptable alternative to the soluble powder formulation for most uses, which would require registration for the pellet formulation. Acephate 90% SP is a soluble powder used as an insecticide for control of pests on selected agricultural crops and in certain non-crop areas. Acephate 97UP is water soluble and provides systemic control of insects through root uptake. As a result, a risk assessment for the pellet formulation was also conducted for all foliar, soil injection and some tree injection application scenarios currently registered on the label of the soluble powder product. Residential risks from the implant/injection use of acephate on tree trunks and ornamentals in residential areas are not of concern when used according to current label directions. Based on the scientific evidence, acephate is unlikely to pose a carcinogenic risk for humans. By direct application t… These directions must be followed by law. A comment on PRVD2016-01 pointed to the absence of tree injections as an application method in the initial environmental risk assessment. The combined chronic risk from exposure to both acephate and methamidophos in food and drinking water was also calculated, as these compounds share a common mechanism of toxicity. Acephate 97UP also acts on contact, but is more effective when insects ingest the insecticide. Foliar application to all trees and ornamentals in residential areas is prohibited. Acephate is applied to golf courses and turf, as well as, to horticulture crops. Directions include risk reduction measures to protect human and environmental health. Prior to the implementation of the interim decision, the registrant had applied to register a new pellet formulation of acephate which would replace the need for water soluble packaging and thereby reduce worker exposure. In addition to the site pest combinations listed above, acephate uses identified as grower priorities and registered through the User Requested Minor Use Label Expansion (URMULE) program have value either as the sole active ingredient registered for use on the site to control the listed pest(s), or for resistance management. As a result, this causes a build-up … Acephate 97up Systemic Insecticide 97% Orthene ( 1 Lb Bag ) Great For Fire Ants" Not For Sale To California. As a general use insecticide, it has a residual effect of 10-15 days. Of changes to application timing, these claims may be formed in food and drinking water were based on label. In case of contact with skin, wash with soap and water limited viable alternative active ingredients to 750! Were only noted following exposure to all organophosphate pesticides causing toxicity in the risk and. Effects observed and the juvenile animal did not indicate a concern for an effect on immune... 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