Friends raise €290.800,- for Hubrecht Institute. Jobs. Bob Roberts 2020-04-16 23:48:49? The Hubrecht Institute is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW), situated on the Utrecht Science Park. The nuclear lamina (NL) is a thin meshwork of filaments that lines the inner nuclear membrane, thereby providing a platform for chromatin binding and supporting genome organization. Hubrecht Institute, NL. Seeing is sequencing: linking phenotypes and genotypes of heterogeneous cancer cells by high-throughput, microscopy-based single cell selection and functionally annotated single cell sequencing. Jop Kind Group Jop Kind Oncode Investigator at Hubrecht Institute My Research. To be announced. Biomedical genomics; Hubrecht Institute. j.kind@hubrecht.eu. Cited by. Jop Kind lab. Miao-Ping Chien. Jop Kind, Junior Group Leader at the Hubrecht Institute. That way, we hope to better understand the relationship between epigenetics and the emergence of new cell types”, says Kind. Their combined citations are counted only for the first article. The following articles are merged in Scholar. Key words: Single-cell genomics, epigenetics, spatial genome organization, bioinformatics, gene-regulation, embryogenesis, tumorigenesis. That knowledge underlines the link between alcohol consumption and cancer. Here For You During COVID-19 NEW! Jop Kind The organization of DNA within the eukaryotic nucleus is important for cellular processes such as regulation of gene expression and repair of DNA damage. Get Funding: Convey the impact of your scientific vision. Annual Scientific Meeting. 13:05. degree at EMBL Heidelberg and conducted her PhD research on the topic of Chromatin and Biomedical Genetics at Hubrecht Institute as a Marie-Curie fellow. Protein–DNA interactions are essential for establishing cell type–specific chromatin architecture and gene expression. Mechanisms underlying cell-fate choice in early embryogenesis Verified account Protected Tweets @; Suggested users Jop Kind leads a Developmental Epigenomics group at Hubrecht Institute, Netherlands. Nederland, © Copyright 2021 Privacypolicy Hubrecht Institute. The researchers want to know when and how cells in the early embryo ‘choose’ what type of cell they will become; whether they will for example become part of the skin or rather become part of the group of cells that forms the supporting embryonic tissue such as the placenta. Network. Geert Kops Group. Publications 23. Scientists from the groups of Puck Knipscheer (Hubrecht Institute) and Ketan J. Patel (MRC Laboratory of Molecular Biology) studied the second line of … Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. 2 day event 04 - 05 Nov. Oncode - CGC Annual Conference: Basic biology meets Cancer research. Year; Systematic protein location mapping reveals five principal chromatin types in Drosophila cells. 12:35. We are employing scDam&T to obtain a better understanding of the epigenetic mechanisms underlying lineage decisions in early embryogenesis, to identify the epigenetic trajectories of single cells that acquire malignant identities in tumorigenesis and to obtain insight into the role of chromatin in DNA double-strand repair. Jop, now Group Leader at … 1 Institute of Epigenetics and Stem Cells (IES), Helmholtz Zentrum München, Munich, Germany. KIT, Royal Tropical Institute. 2 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. Ester Frische; Mariëlle Harlé; Yuva Oz; Jacqueline Staring; Peter Thijssen; More information will follow. 2 day event 19 - 20 Apr. Puck Knipscheer Group. Go to Website Navigation: Home; about narcis; login; Nederlands; contact. Biography. This type of DNA damage can have an endogenous cause, but it can also be caused by external influences, such as high dosages of chemotherapy in cancer. Sort by citations Sort by year Sort by title. Former EMBL Genome Biology PhD student, Jop Kind, has been selected as this year’s John Kendrew Young Scientist Award winner for pioneering postdoctoral work in establishing novel technologies to … Save the date! Kind’s group previously developed advanced techniques with which they can study epigenetics in a single cell and match it with the cell’s choice of identity. PMID: 32350457 DOI: 10.1038/s41596-020-0314-8 Overview; Fingerprint; Network; Research Output (8) Similar Profiles (28) If you made any changes in Pure these will be visible here soon. Best Cities for Jobs 2020 NEW! Puck Knipscheer and Jop Kind, both group leader at the Hubrecht Institute and Oncode investigator, individually receive a prestigious European Research Council (ERC) Consolidator Grant. Jop Kind. jop kind Hubrecht Institute Verified email at hubrecht.eu. Molecular biologist dr. Jop Kind (1978) joined the Van Steensel lab as a postdoc after a highly successful PhD at the EMBL. Puck Knipscheer Group. Since October 2014 he is Junior Group Leader at the Hubrecht Institute. Erasmus University Medical Center/ UFO Biosciences, NL . 2 Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Center Utrecht and Oncode Institute, Utrecht, The Netherlands. Duplicate citations. Jop Kind, Junior Group Leader at the Hubrecht Institute. 23. 23. Silke J. The researchers are each given two million euros to strengthen their research groups and continue their innovative research in the next 5 years. jop kind. * Correspondence: j.kind@hubrecht.eu † These authors contributed equally to this work. 3,331. Cited by. j.kind@hubrecht.eu. Reads . About. Save the date for our Annual Conference! Additionally, they will investigate whether there are other, currently unknown pathways involved in repairing ICLs. A major interest in the group is how gene-expression control is achieved in early embryogenesis. More information. 3584 CT Utrecht Hubrecht Institute, NL. Projects 1. Jop is currently an associate professor at the Hubrecht Institute in Utrecht where his lab continues to develop new techniques to single-cell profile gene-regulation to obtain better insights into the mechanisms that govern cell fate choice in development and disease. Follow. Verified email at imba.oeaw.ac.at - Homepage. Projects 1. Fingerprint. The Kind group uses a combination of single-cell genomics and microscopy methods to study the role of chromatin and epigenetics in gene-regulation control, with a focus on early mouse embryonic development and tumorigenesis. 13:35. Jop Kind is group leader at the Hubrecht Institute and Oncode Investigator. Jop Kind is group leader at the Hubrecht Institute and Oncode investigator. Spatiotemporal regulation of genomic function; Hubrecht Institute. 7 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. 12:35. Title. Jop Kind received his PhD from the Radboud University Nijmegen in 2008 for his work on chromatin and gene expression in the research group of Asifa Akhtar at EMBL Heidelberg. Molecular mechanisms and regulation of DNA repair; Hubrecht Institute. The group focuses on a specific type of DNA damage called a DNA interstrand crosslink (ICL). Former EMBL Genome Biology PhD student, Jop Kind, has been selected as this year’s John Kendrew Young Scientist Award winner for pioneering postdoctoral work in establishing novel technologies to map chromatin domains in single cells. Sara is now working as a computational biologist in the lab of Jop Kind at the Hubrecht Institute (Netherlands). Wouter de Laat Group. 2016: Group Leader, Hubrecht Institute, Utrecht, The Netherlands. Institute of Molecular Biotechnology, Austrian academy of science. Uppsalalaan 8 Over 17 years of experience in Molecular Biology, Yuva completed her MSc. “That allows us to make a family tree of the various epigenetic stages that preceded the choice the cell eventually made. Genomic regions contacting the NL are lamina associated domains (LADs), which contain thousands of genes that are lowl … EMBL alumnus Jop Kind’s research focuses on the role of DNA organisation in genome stability, cell development and disease. The research group of Knipscheer researches DNA repair: how does our genetic material remain stable and how do we prevent the development of genetic diseases such as cancer? Online event. 2 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. Knipscheer’s group will use the ERC grant to further research this pathway. Sort. PMID: 31118510 PMCID: PMC6546605 That knowledge underlines the link between alcohol consumption and cancer. cells Review Lamina Associated Domains and Gene Regulation in Development and Cancer Silke J. 7 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. Seeing is sequencing: linking phenotypes and genotypes of heterogeneous cancer cells by high-throughput, microscopy-based single cell selection and functionally annotated single cell sequencing. 7 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. Wednesday 22 July. Contact Information Mariëlle Harlé Other Events. A. Lochs †, Samy Kefalopoulou † and Jop Kind * Oncode Institute, Hubrecht Institute–KNAW and University Medical Center Utrecht, 3584 Utrecht, He made visible how 6 feet of DNA is dispersed in a cell nucleus of 10 micrometres. Jop Kind. These topic labels come from the works of this person. This "Cited by" count includes citations to the following articles in Scholar. 3584 CT Utrecht See what employees say about what it's like to work at Hubrecht Institute. Accurate repair of DNA damage is critical for the maintenance of genomic integrity. Jop Kind, group leader at the Hubrecht Institute, has been awarded a NWO Vidi-grant. Save the date for our Annual Conference! The early mammalian conceptus (blastocyst) contains two supporting extraembryonic tissues - the trophectoderm and the primitive endoderm (PrE) - that encase and guide the epiblast (Epi) to eventually form the all body. Kind’s work has paved the way for the development of powerful technologies to map chromatin, or balled-up DNA, in single cells, earning him this year’s John Kendrew Award. By Jop Kind, Hubrecht Institute. Jop Kind Group. Molecular biologist dr. Jop Kind (1978) joined the Van Steensel lab as a postdoc after a highly successful PhD at the EMBL. 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